Hall Categories:

Podium: Neural bases

9 RESULTS

A physiologically-based model for pitch based on fluctuations in auditory-nerve responses: Effects of sensorineural hearing loss

Laurel H. Carney11Depts. of Biomedical Engineering and Neuroscience, University of Rochester, Rochester, New York, USA The goal of this project is to explore representations of pitch using physiological models for auditory-nerve (AN) and midbrain (inferior colliculus, IC) neurons. An established model for ‘central pitch’ (Goldstein, 1973, JASA) requires a robust neural response profile that corresponds …

An encoding-decoding method for studying perception with hearing loss

Jiayue Liu1, Josh Stohl2, Enrique Lopez-Poveda3, Tobias Overath11 Department of Psychology & Neuroscience, Duke University, Durham, US2 North American Research Laboratory, MED-EL Corporation, Durham, US3 Instituto de Neurociencias de Castilla y León, Universidad de Salamanca, Salamanca, Spain ‘Hidden hearing loss’ has inspired a wealth of research, including what and how morphological changes in the auditory periphery might cause …

Diagnostic tools for differing sites of lesion

Neil J. Ingham1, Clarisse H. Panganiban1, Navid Banafshe1, Christopher J. Plack2, Karen P. Steel11Wolfson Centre for Age-Related Diseases, King’s College London, London SE1 1UL, UK2Manchester Centre for Audiology and Deafness, The University of Manchester, Manchester M13 9PL, UK Any clinical trial for hearing treatments would benefit from improved stratification of the participants according to the …

Maladaptive central auditory plasticity: A critical arbiter linking cochlear neural degeneration with suprathreshold hearing disorders

Daniel B. Polley1,2 1Eaton-Peabody Laboratories, Mass. Eye and Ear, Boston, USA2Department of Otolaryngology, Harvard Medical School, Boston, USA Hearing disorders are typically studied and treated from the perspective of wanting to make inaudible sounds audible. Yet three of the most common and debilitating adult hearing complaints reflect just the opposite problem: not what persons cannot hear, …

Cochlear synaptopathy in noise-induced and age-related hearing loss

M. Charles Liberman11Eaton-Peabody Laboratories, Mass. Eye and Ear, Boston, USA Most hearing impairment in adults arises from damage to the sensory cells and/or nerve fibers of the inner ear.  This talk will summarize recent research on animal models and human autopsy material showing that, in both noise-induced and age-related hearing loss, the synaptic terminals of cochlear nerve …